Events / ILST Seminar: Sunghye Cho

ILST Seminar: Sunghye Cho

September 17, 2021
1:30 PM - 2:30 PM

3401 Walnut Street, Room 401B, 3401 Walnut Street, Philadelphia, Pennsylvania 19104

Sunghye Cho
Linguisitc Data Consortium (LDC)


Automated acoustic and lexical analyses of natural speech in patients with Alzheimer’s disease


Speech production is a complex behavior, involving activation of multiple regions of the brain; thus, examining speech production provides opportunities to identify disease markers. Since Alzheimer’s Disease (AD) accounts for up to 80% of patients with dementia, affecting over 50 million people worldwide, much attention has been paid to cognitive changes of AD, including the linguistic domain. In this talk, I will present a series of AD-related projects that identify specific language biomarkers of AD, Mild Cognitive Impairment (MCI), and logopenic variant primary progressive aphasia (lvPPA), which is a non-amnestic type of AD, using our automated lexical and acoustic pipelines. I will also show correlations with our language variables and traditional clinical ratings, disease severity predition, and longitudinal changes in patients’ speech. I will also present results of automatic classification of patient groups with our language features. Lastly, I will present the application of our automated pipelines to speech samples of standardized neuropsychological tests.