We have implemented a weekly quality assurance (QA) protocol in which we assess the stability of the fMRI signal from the Cima.X scanner using the 64-, 32-, and 20-channel head coils and both standard Siemens and CMRR multi-band EPI pulse sequences. The scan protocol is based on the recommendation of John Pyles and colleagues (Pyles et al, OHBM 2020) found here: https://sites.google.com/view/mri-facility-qa. Imaging is done on a FUNSTAR phantom in the 64- and 32-channel coils using custom 3D-printed phantom holders (I’m quite proud of the holders; I’ll make a detailed post bragging about them later). Stability is assessed using the Functional Imaging Federated Informatics Research Environment (FBIRN; see Friedman & Glover, 2006) QA metrics, which includes temporal signal to noise ratio (SNR), signal-to-fluctuation noise ratio (SFNR), and mean ghost percentage. I’ve been using a docker-ized version of the FBIRN QA scripts provided by Dr. Chandana Kodiweera of the Dartmouth Brain Imaging Center found here: https://hub.docker.com/r/diffdocker/fbirnqa.

The plan is to post detailed weekly QA measures to a shared Box folder that will be made available to MindCORE researchers upon request. I’ll post summary graphs of SNR, SFNR, and mean ghost percentage for each of the head coils and each of the scan sequences in a separate post and will make further regular posts with updated longitudinal data. For now, I’ll include the output of the FBIRN QA for one of the scans with the 64-channel coil to give you a flavor of the types of measures we’re tracking with these scans.


Phantom QA results for 64-channel CMRR Multi-band factor = 3 scan (4/8/25)

Odd-even difference image

Mean image

Standard deviation image

SFNR image

Acquisition parameters:

dimensions 106x106x69x200
spacing 2mmx2mmx2mm
gap 0mmx0mmx0mm
scanner Cima.X
psdname
examnumber d9a9a0b2-2cfa-4d
studyid Stability_20250408
seriesnumber 6
runnumber 1-200
scanningsequence GR/EP
sequencevariant SK
magneticfield 3
description ses-64ch_func-bold_acq-cmrrstd_task-tsnr
scandate 2025-04-08
scantime 09:48:06
tr 2000
te 30
operator
flipangle 79
prescribedslicespacing 2
frequencydirection 1
acquisitionmatrix 106 106
bandwidth 192.284
receivecoilname HeadNeck_64_CS
transmitcoilname Body
institution THE UNIVERSITY OF PENNSYLVANIA
examdescription ACTIVE KIRWAN
scanner AWP213018
scannermanufacturer Siemens Healthineers
scannermodelname MAGNETOM Cima.X
ti
protocolname ses-64ch_func-bold_acq-cmrrstd_task-tsnr
institutionaddress UPenn
institutionaldepartmentname MindCORE Neuroimaging Facility
acquisitiondatetime 20250408094804.300000
volumetricproperties DISTORTED
scanoptions PFP/FS/PER
mracquisitiontype 2D
sequencename epfid2d1_106
angioflag N
numaverages 1
imagingfrequency 123.253286
imagednucleus 1H
spacingbetweenslices 2
numphaseencodingsteps 106
echotrainlength 80
percentsampling 100
percentphasefieldofview 100
scannerserialnumber 213018
softwareversions syngo MR XA61
triggertime
beatrejectionflag N
cardiacnumberofimages 1
inplanephaseencodingdirection COL
variableflipangleflag N
sar 0.01584647112671
contentqualification RESEARCH
acquisitionnumber 1
instancenumber 1
numtemporalpositions 200
imagecomments Not for diagnostic use, Unaliased MB3/PE3/LB
samplesperpixel 1
photometricinterpretation MONOCHROME2
rows 106
columns 106
bitsallocated 16
bitsstored 16
highbit 15
lossyimagecompression 00
echonumber 0
pixelbandwidth 1814

References

Friedman, L., & Glover, G. H. (2006). Report on a multicenter fMRI quality assurance protocol. Journal of Magnetic Resonance Imaging, 23(6), 827–839. https://doi.org/10.1002/jmri.20583

Pyles, J., Verstynen, T., Magerkurth, J., Weiskopf, N., Golay, X., & Inglis, B. (2020, June). 2019 MR Facility Quality Assurance: A publicly available protocol. Abstract presented at the Organization for Human Brain Mapping (OHBM) Annual Meeting. https://www.humanbrainmapping.org/files/2020/OHBM_2020_Virtual_Abstracts_2.pdf