Events / CNI Seminar: Donald Wilson

CNI Seminar: Donald Wilson

October 23, 2018
11:30 AM - 1:00 PM

Barchi Library (140 John Morgan Building), 3620 Hamilton Walk, Philadelphia, PA 19104

Donald Wilson
Department of Neuroscience and Physiology


Smell in context: The role of top-down feedback and dynamic networks in olfaction


Sensory cortices process afferent input in the context of activity from a wide variety of other inter-cortical inputs. These top-down inputs provide information about expectation, recent history and multisensory associations that modulate the processing of bottom-up sensory input. Importantly the balance between bottom-up and top-down inputs in driving sensory cortical neurons is state- and behavior-dependent. Here I will describe piriform cortical processing of odors and odor-perceptual objects in such a dynamic context, explore the role of acetylcholine in modulating these intercortical connections, and highlight the importance of flexible “connectomes” in normal memory and perception.


A pizza lunch will be served.